A Review on Cardioprotective Effect of An Antioxidant, Vitamin-E Against Myocardial Infarction

Abstract

Vitamin E (Vit E), an antioxidant, is a compound that has an important role in maintaining health because it can capture free radical molecules that inhibit oxidative reactions in the body, is considered to prolong survival in patients and animals. Myocardial infarction (MI), known as a heart attack, is the formation of a necrosis in heart muscle cells following inadequate blood supply. This study tested the hypothesis that early treatment with Vit E reduces mortality because of its protective effects against myocardial infarction by arresting free radical molecules and reactive oxygen species that cause degenerative diseases. Miocardial Infarction is one of the clinical manifestations of coronary heart disease, which is a major cause of morbidity and mortality worldwide. Early mortality rate of 30 days in acute MI patients is 30% with more than half deaths before the patient reaches the hospital.