Sudden Visual Loss as Initial Presentation of Chronic Myeloid Leukemia : A Case Report

Abstract

A healthy, 26-year-old Chinese gentleman presented with sudden onset of reduced vision in the right eye associated with floaters. He claimed to be lethargic for the past three weeks prior to presentation. There was no history of other constitutional and systemic symptoms. He has no significant family history of malignancy or eye problem. Examination revealed right best corrected visual acuity (BCVA) of 6/36 and left BCVA was 6/9. Anterior segment examinations were normal. However, funduscopy revealed bilateral hyperemic optic discs swelling, dilated and tortuous retinal veins with multiple dot and blot haemorhages including Roth spots. There was also vitreous haemorhage in the right eye. The other cranial nerves were normal. Systemic examination revealed no organomegaly. Blood investigations were suggestive of Chronic Myloid Leukemia (CML) in chronic phase.