Hazirah binti Abdul Radzak
http://unisep.lib.unishams.edu.my/xmlui/handle/123456789/6422
2024-03-29T09:02:42ZKnowledge, Attitudes and Practices Towards COVID-19 Among Public in Malaysia
http://unisep.lib.unishams.edu.my/xmlui/handle/123456789/28424
Knowledge, Attitudes and Practices Towards COVID-19 Among Public in Malaysia
Hazirah Abdul Razak; Ahmad Hafiz Alauddin Che Ini; Ameerul Mukmin Khairul Anuar; Mohammad Faris Najmi Mohd Norzri; Muhammad Abdurrahman Ismail; Nur Hannah Md Jelani; Farah Wahida Amran; Bahirah Ramzee; Omar Mihat; Harif Fadzilah Che Hashim
The Government of Malaysia have set and implemented various Standard Operating Procedures (SOP) as an effort to mitigate the outbreak of Coronavirus disease 2019 (COVID-19). Compliance and cooperation of Malaysian towards SOP are an indicator of the effectiveness of these mitigation measures. The aim of this research was to study the knowledge, attitudes and practices towards COVID-19 among public in Malaysia. A cross-sectional online survey of 419 Malaysian residents was conducted between 1st May 2021 to 10th June 2021. The survey instrument consisted of demographic characteristics, 11 items on knowledge, 10 items on attitude and 9 items on practices. Descriptive statistics, chi-square tests, t-tests and one-way analysis of variance (ANOVA) were used to analyze the data obtained.
2021-11-01T00:00:00ZExercise and Obesity: Activation of Antioxidative Pathway Against Oxidative Stress
http://unisep.lib.unishams.edu.my/xmlui/handle/123456789/28423
Exercise and Obesity: Activation of Antioxidative Pathway Against Oxidative Stress
Hazirah Abdul Razak; Lee Li Li; Nabilah Sainuddin; Rusmaliza Hamzah; Natasha Farhana Zainol; Omar Mihat
Obesity is now acknowledged as a primary health burden which impact quality of life heavily due to its various complications. It is a chronic disease of multifactorial origin. Growing evidence proposes that one of the critical factors linking obesity with its associated complications is oxidative stress. Obesity induces systemic oxidative stress which causing the disordered production of adipokines that contributes to the metabolic syndrome development. They are more sensitive towards C-reactive protein (CRP) and other oxidative damage biomarkers. In contrast, the level of antioxidants is glutathione (GSH), which acts against free radicals and reactive oxygen species (ROS) in detoxification of xenobiotic compounds. Moreover, glutathione peroxidase (GPx), one of the most abundant in its family is the most effectual one against oxidant stress in erythrocytes and has some essential functions in phagocytic cells. Besides, it is also in charge of the removal of intracellular hydroperoxides. Therefore, this review attempts to evidence the role of oxidative stress due to obesity as well as antioxidants as the potential opposition to this event as promising interventional theraphy to manage obesity.
2021-11-01T00:00:00ZTotal Phenolic Content and Antioxidant Activities of Corchorus Capsularis and Stevia Rebaudiana Extracts
http://unisep.lib.unishams.edu.my/xmlui/handle/123456789/11872
Total Phenolic Content and Antioxidant Activities of Corchorus Capsularis and Stevia Rebaudiana Extracts
Hazirah binti Abdul Radzak; Siti Sarah S, Dr.; Syakinah A, Dr.; Siti Atika J, Dr.; Zainal B, Dr.; Abdah MA
The purposes of this study were to determine total phenolic content (TPC) and antioxidant activities of C.capsularis and S.rebaudiana. Methodology: C.capsularis was extracted successively with methanol and chloroform methanol separately while S.rebaudiana was extracted using methanol and chloroform solvent. The plant extracts were used to conduct various antioxidant assays. TPC assay using Folin- Ciocalteu method was used to assess the presence of phenolic compounds in each sample. The extracts samples were also subjected to assess their potential antioxidant activities through DPPH, ABTS and FRAP assay. The present study showed that both methanol extract of C.capsularis and S.rebaudiana had highest TPC, followed by chloroform extract of S.rebaudiana and chloroform methanol extract of C.capsularis. Next, the DPPH radical iscavenging assay was found to be higher in the methanol extract of S.rebaudiana at the concentration of 154.67µg/ml. The cation radical scavenging activity, measured by ABTS assay was shown that methanol extract of S.rebaudiana (278µg/ml) had the lowest EC50 as compared to the other samples. Interestingly, among the various samples, the methanol extract of S.rebaudiana demonstrated a very significant antioxidant activity in FRAP assay (p<0.05). The results of the present study
showed that all the extract samples contain significantly high phenolic compounds with superior antioxidant activity as evidence by scavenging of free radical including DPPH and ABTS. In conclusion, it is conceivable that the C.capsularis and S.rebaudiana have shown potential as sources of natural antioxidants.
2017-06-01T00:00:00Z