The International Journal of Medicine and Sciences - KUINOnline Journal from Kulliyyah of Medicine & Health Sciences (KUIN)http://unisep.lib.unishams.edu.my/xmlui/handle/123456789/118352024-03-29T14:19:07Z2024-03-29T14:19:07ZCorticosteroid-Induced Glaucoma in Severe Vernal Keratoconjunctivitis : Tube or TrabeculectomyNew Swe Hui, Dr.Norshamsiah Md Din, Dr.Ropilah binti Abdul Rahman, Assoc. Prof. Dr.Suresh Kumar Vasudevan, Dr.http://unisep.lib.unishams.edu.my/xmlui/handle/123456789/118732020-02-10T14:40:41Z2017-06-01T00:00:00ZCorticosteroid-Induced Glaucoma in Severe Vernal Keratoconjunctivitis : Tube or Trabeculectomy
New Swe Hui, Dr.; Norshamsiah Md Din, Dr.; Ropilah binti Abdul Rahman, Assoc. Prof. Dr.; Suresh Kumar Vasudevan, Dr.
Vernal keratoconjunctivitis (VKC) is a severe form of ocular allergy that affects primarily children and young adults living in areas with warm climates. While VKC is self-limiting, chronic forms in Asian eyes may be at higher risk of permanent visual impairment because of complications such as corneal scarring, cataract formation and glaucoma secondary to corticosteroid therapy. The incidence of glaucoma secondary to corticosteroid therapy is 2–7%, most often requiring filtering surgery. We present a case demonstrating the outcome of surgery in a patient; trabeculectomy in one eye versus
Tube/shunt in the other.
2017-06-01T00:00:00ZTotal Phenolic Content and Antioxidant Activities of Corchorus Capsularis and Stevia Rebaudiana ExtractsHazirah binti Abdul RadzakSiti Sarah S, Dr.Syakinah A, Dr.Siti Atika J, Dr.Zainal B, Dr.Abdah MAhttp://unisep.lib.unishams.edu.my/xmlui/handle/123456789/118722020-02-10T14:41:26Z2017-06-01T00:00:00ZTotal Phenolic Content and Antioxidant Activities of Corchorus Capsularis and Stevia Rebaudiana Extracts
Hazirah binti Abdul Radzak; Siti Sarah S, Dr.; Syakinah A, Dr.; Siti Atika J, Dr.; Zainal B, Dr.; Abdah MA
The purposes of this study were to determine total phenolic content (TPC) and antioxidant activities of C.capsularis and S.rebaudiana. Methodology: C.capsularis was extracted successively with methanol and chloroform methanol separately while S.rebaudiana was extracted using methanol and chloroform solvent. The plant extracts were used to conduct various antioxidant assays. TPC assay using Folin- Ciocalteu method was used to assess the presence of phenolic compounds in each sample. The extracts samples were also subjected to assess their potential antioxidant activities through DPPH, ABTS and FRAP assay. The present study showed that both methanol extract of C.capsularis and S.rebaudiana had highest TPC, followed by chloroform extract of S.rebaudiana and chloroform methanol extract of C.capsularis. Next, the DPPH radical iscavenging assay was found to be higher in the methanol extract of S.rebaudiana at the concentration of 154.67µg/ml. The cation radical scavenging activity, measured by ABTS assay was shown that methanol extract of S.rebaudiana (278µg/ml) had the lowest EC50 as compared to the other samples. Interestingly, among the various samples, the methanol extract of S.rebaudiana demonstrated a very significant antioxidant activity in FRAP assay (p<0.05). The results of the present study
showed that all the extract samples contain significantly high phenolic compounds with superior antioxidant activity as evidence by scavenging of free radical including DPPH and ABTS. In conclusion, it is conceivable that the C.capsularis and S.rebaudiana have shown potential as sources of natural antioxidants.
2017-06-01T00:00:00ZRole of Human Papilloma Virus in Head And Neck MalignancyPookamala S., Dr.http://unisep.lib.unishams.edu.my/xmlui/handle/123456789/118702020-02-10T14:41:55Z2017-06-01T00:00:00ZRole of Human Papilloma Virus in Head And Neck Malignancy
Pookamala S., Dr.
Human papilloma virus has been routinely implicated in the carcinogenesis of uterine cervix, vagina, vulva and anal region. Recently over the past two decades, it has been found that HPV virus is also responsible for the carcinoma of tonsil and base
tongue region in the oropharynx. Interestingly the main viral strain that is involved in carcinogenesis of uterine cervix and oropharyngeal region is HPV 16. Currently, the incidence of oropharyngeal malignancy is increasing alarmingly and more
than 80% of such malignancies are due to high risk HPV virus infection. So a literature review was done to analyse data on disease prevalence, disease behaviour and treatment outcome of HPV positive Head & Neck malignancy. It was found that
unlike non HPV related Head & Neck carcinoma which usually affects older age group, HPV positive head and neck malignancy tend to affect younger age group. Individuals with HPV positive oropharyngeal malignancy tend to have oral sex and have multiple sexual partners. Such sexual practice, explains the reason for the confinement of HPV positive malignancy mainly to the oropharyngeal region in head and neck. Tumour has less aggressive course and they show better response to treatment. Overall the tumour affects younger individuals and shows better treatment response. All these favourable factors have opened up scope for treatment de-intensification, targeted therapy and cancer prevention using HPV vaccine.
2017-06-01T00:00:00ZUndergraduate Students’ Learning Curve in Formulating Differential Diagnosis of Substance-Induced Psychotic DisorderMohd Jamil Y, Assoc. Prof. Dr.Nur Hadibah H, Dr.Puteri Nurul Najwa MA, Dr.http://unisep.lib.unishams.edu.my/xmlui/handle/123456789/118652020-02-10T14:42:35Z2017-06-01T00:00:00ZUndergraduate Students’ Learning Curve in Formulating Differential Diagnosis of Substance-Induced Psychotic Disorder
Mohd Jamil Y, Assoc. Prof. Dr.; Nur Hadibah H, Dr.; Puteri Nurul Najwa MA, Dr.
Two cases from undergraduate case studies were presented. The challenges in diagnosis were highlighted. Invariably, the differential diagnosis of substance-induced psychotic disorder is often misleading and instable over time. Therefore, a systematic framework using multidimensional grid was proposed. Finally, the differential diagnoses were discussed.
2017-06-01T00:00:00Z